When you elevate your brows, you elevate your Mood


Sadness, stress and fatigue can cause heavy eyes, dropped brows and forehead wrinkling "omega melancholia".  After treating patients with Botox ® for more than a decade, patients have taught me that Botox® gives them more than cosmetic gains, they gain a sense of well-being. Medical Literature now supports Botox® use to help depression. `Ally Broderick PA

Expression of an emotion intensifies the emotion. Expressed fatigue, sadness begets fatigue and sadness. Botox® may interrupt this mood cycle.

Botox® relaxes tightened muscles around the eyes. A rested, more youthful appearance is created when brow muscles release following a single treatment with Botox®. Sure, changing facial expression may positively change how others respond to you, but current research shows facial expression change how you respond -to yourself. Current research suggests that facial expression both regulate and reveal mood With conservative Botox®, your facial muscles are made relaxed without the tell-tale signs of a Botox®appearance.



Botox®& Depression: Journal of Psychiatric Research 

Botox® for depression? Several studies including a 2014 double-blind randomized placebo control study indicated, yes.

Journal of Psychiatric Research 52 (2014) 1-6; showed 52% and 15% response rate in the treatment versus placebo groups. There are currently, two such studies. Also, there are numerous case studies that reach very similar conclusions of efficacy. Wollmer's 2012 research, also published in the Journal of Psychiatric Research, showed that Botox® significantly improved the mood of moderately depressed patients over a 16 week study. Wollmer also gave Botox® injections to an equal-sized control group to make sure the improvement wasn't just a placebo effect from getting treatment. When Wollmer sought volunteers for the study, he didn't tell them they might be getting Botox® — to make sure they didn't volunteer for cosmetic reasons. Also, he didn't know which patients were receiving the real Botox® treatment and which an empty solution. "In the end, those who became better were those who had gotten the Botox® injections," he says. Both studies above were non-pharmaceutical funded. 

Research published in the Journal of Dermatologic Surgery found a link between the use of Botox® and a decrease in depression from relaxing the muscles that cause frown lines or scowl. Yet even more evidence has emerged to support the positive effects of Botox® for patients undergoing treatment for depression.

In another, still-unpublished study in Austin, husband-and-wife researchers dermatologist Jason Reichenberg and Psychiatrist Michelle Magid found similarly positive and long-lasting results."That makes you wonder if we're changing something chemically, breaking the cycle of active depression," said Reichenberg.

These studies support the concept that facial musculature not only express, but also regulate mood.

According to the World Health Organization, depression is one of the leading causes of disability in the world, affecting 121 million people. Negative emotions, like anger, fear and sadness. prevalent in depression have been shown to be associated with activation of the muscles in the glabellar region (frown muscles) of the face. 

  Two weeks after treatment with Botox

Two weeks after treatment with Botox


Can Depression be Treated with Botox?

Study co-author Dr. Norman E. Rosenthal, MD, Clinical Professor of Psychiatry at Georgetown Medical School, commented, “This research is groundbreaking because it offers those who suffer from depression and their doctors an entirely new approach to treating the condition - one that doesn’t conflict with any other treatments.”



Botox® has long been a part of my cosmetic tools, softening lines and turning back the clock. But it took me a while to realize its potential to do so much more. It is a very selective inhibitor of muscles, allowing one to pinpoint which muscles to treat. As I became aware of an important feedback loop between the brain and the muscles of facial expression, I began to suspect that Botox® could help control the flow of negative emotions, quieting the facial muscles that really express negativity, the muscles between the eyebrows that help create the frown. Could I change moods and help depression simply by preventing a negative facial expression?
— The Face of Emotion: How Botox® Affects Our Moods and Relationships by Eric Finzi, MD

For more informationhttp://www.botoxfordepression.com/


1 Wollmer MA, de Boer C, Kalak N, Beck J, Götz T, Schmidt T, Hodzic M, Bayer U, Kollmann T, Kollewe K, Sönmez D, Duntsch K, Haug MD, Schedlowski M, Hatzinger M, Dressler D, Brand S, Holsboer-Trachsler E, Kruger TH. (2012). Facing depression with botulinum toxin: a randomized controlled trial. J Psychiatr Res, 46, 574-81. doi: 10.1016/j.jpsychires.2012.01.027.

2 Finzi, Eric, and Norman E. Rosenthal. "Treatment of Depression with OnabotulinumtoxinA: A Randomized, Double-blind, Placebo Controlled Trial." Journal of Psychiatric Research, Volume 52 May 2014. Print.

3 Hexsel D, Brum C, Siega C, Schilling-Souza J, Forno TD, Heckmann M, Rodrigues TC. (2013). Evaluation of Self-Esteem and Depression Symptoms in Depressed and Nondepressed Subjects Treated with OnabotulinumtoxinA for Glabellar Lines. Dermatol Surg. doi: 10.1111/dsu.12175.

4 Lewis MB, Bowler PJ. (2009). Botulinum toxin cosmetic therapy correlates with a more positive mood. J Cosmet Dermatol., 8, 24-6. doi: 10.1111/j.1473-2165.2009.00419.x.